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Hypercholesterolemia Symptoms, diagnosis and treatment BMJ Best Practice.
Complications include myocardial infarction, ischemic cardiomyopathy, sudden death, ischemic stroke, erectile dysfunction, peripheral vascular disease, and acute limb ischemia. Risk factors for secondary hypercholesterolemia in industrialized populations include a sedentary lifestyle and a diet characterized by the excessive consumption of saturated fats, trans-fatty acids, and cholesterol.
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Familial hypercholesterolemia: MedlinePlus Medical Encyclopedia.
Men and women with familial hypercholesterolemia typically are at increased risk of early heart attacks. Risk of death varies among people with familial hypercholesterolemia. If you inherit two copies of the defective gene, you have a poorer outcome. That type of familial hypercholesterolemia does not respond well to treatment and may cause an early heart attack.
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Hypercholesterolemia Genetics Home Reference.
Hypercholesterolemia results when low-density lipoprotein receptors are unable to remove cholesterol from the blood effectively. Researchers are working to identify and characterize additional genes that may influence cholesterol levels and the risk of heart disease in people with hypercholesterolemia. Learn more about the genes associated with hypercholesterolemia.
Hypercholesterolemia Wikipedia.
Genetic abnormalities are in some cases completely responsible for hypercholesterolemia, such as in familial hypercholesterolemia, where one or more genetic mutations in the autosomal dominant APOB gene exist, the autosomal recessive LDLRAP1 gene, autosomal dominant familial hypercholesterolemia HCHOLA3 variant of the PCSK9 gene, or the LDL receptor gene.
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Definition of Hypercholesterolemia.
Persons with familial hypercholesterolemia can reduce their risk by adhering to a very low cholesterol diet under a doctor's' supervision, and may also need to take medications that reduce their cholesterol level. Familial hypercholesterolemia is recognizable in childhood. Children and other relatives at risk for familial hypercholesterolemia can be screened checked for the condition.
What is Hypercholesterolemia?
However, whether or not a lipid profile is considered safe or not also depends on whether a person is at risk of or has heart disease. Patients diagnosed with hypercholesterolemia are advised to modify their diet and engage in regular physical activity.
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